Comparison of Neutralizing Sars Cov-2 Igg Antibody Levels in Hospitalized Patients at Dr. Mohammad Hoesin Palembang Hospital

ABSTRACT COVID-19 is an acute respiratory disease that spreads rapidly throughout the world caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Published research on levels of SARS-CoV-2 antibodies in hospitalized patients still limited. Research sero-epidemiology and its correlation with clinical severity needed as a database for pandemic governance, especially neutralizing antibodies. This study was designed to compare IgG SARS CoV-2 tenth day various at RSUP Dr. Mohammad Hoesin Palembang. observational-analytic cross-sectional design. The conducted isolation ward RSMH Palembang from December 2021 March 2022. level measured confirmed COVID-19. Differences values were tested Mann Whitney test. effect confounding variables this using bivariate multivariate tests form chi-square test multiple linear regression scale dependent variable. included 50 patients, consisting 22 mild-moderate 28 severely-critically ill. Bivariate analysis showed there no significant difference between two groups. From data ROC curve, cut-off point predicting 500 AU/mL. more than AU/mL causes increased risk 3.69 (95% CI 1.13-11.98) times suffer severe-critical Serum found be significantly higher symptoms hospital. Keywords: COVID-19,